Oxidative damage is caused by free radicals and reactive oxygen species, mostly generated endogenously. Currently, there is great interest in finding antioxidants from natural sources to minimize oxidative damage to cells. In this article flavonoid content, total phenolic content and antioxidant activities of Hydroalcoholic extracts of the Bark of Erythrina indica were measured. Total phenolic content was assessed by the Folin–Ciocalteau assay whereas antioxidant activities were assessed by measuring the ability of the extracts to scavenge the Super oxide free radical and DPPH Free radicals, reducing power Method by FeCl3, Phosphomolybdenum assay (P–Mo). Total Phenolic content and Flavonoid content of Hydroalcoholic (50%) extract of Bark of Erythrina indica (1mcg/ml) was found to be 35.541±0.019 mcg/mg of Gallic acid equivalent to phenol and 330±0.0010 mcg/mg of Rutin equivalent respectively. This extract exerted significant antioxidant activity as evidenced by its DPPH free radical scavenging (IC50= 227.013±0.565 µg/ml.). The reducing power by fecl3 of Erythrina indica Hydroalcoholic (50%) extract increased with increase in concentration and superoxide free radical scavenging activities (IC50= 96.836±1.95 µg/ml) increased in concentration dependent manner. The results obtained in the present study indicate that Erythrina indica is a potential source of Antioxidants.
Loading....